This includes any possible side effects not listed in this leaflet. The overall safety of COVID-19 Vaccine AstraZeneca is based on an interim analysis of pooled data from four clinical trials conducted in the United Kingdom, Brazil, and South Africa. 0000053643 00000 n It is a summary of information about the drug and will not tell you everything about the drug. endstream endobj startxref 3. This medicine contains less than 1 mmol sodium (23 mg) per dose of 0.5 ml. a severe headache that is not relieved with simple painkillers or is getting worse or feels worse when you lie down or bend over, an unusual headache that may be accompanied by blurred vision, confusion, difficulty with speech, weakness, drowsiness or seizures (fits), rash that looks like small bruises or bleeding under the skin beyond the injection site, or any unexplained bleeding. Well send you a link to a feedback form. The majority of recipients were White (75.5%), 10.1% were Black and 3.5% were Asian; 55.8% were female and 44.2% male. How to store COVID-19 Vaccine AstraZeneca 6. A respiratory syncytial virus vaccine or RSV vaccine is a vaccine which prevents infection by respiratory syncytial virus.As of 2023, no licensed vaccine against RSV exists.. The AstraZeneca vaccine is safe and effective at protecting people from the extremely serious risks of COVID-19, including death, hospitalization and severe disease. Oops! If you experience any of the following from around 4 days after vaccination you should seek medical advice urgently: Tell your doctor, pharmacist or nurse if you experienced a blood clot occurring at the same time as low levels of platelets after receiving a previous dose of the vaccine. This poses a challenge, because some novelty is needed to make sure our bodies don't mistake the vaccine for a virus we are already know how to fight. This medicinal product has been given authorisation for temporary supply by the UK Department of Health and Social Care and the Medicines & Healthcare products Regulatory Agency. CLS is a serious, potentially fatal condition causing fluid leakage from small blood vessels (capillaries) resulting in rapid swelling of the arms and legs, sudden weight gain and feeling faint (low blood pressure). Consumer Information. dwS(V"2G %[CA+|}e9;(al-U c9.3T@k w This has been reported very rarely after vaccination with COVID-19 Vaccine AstraZeneca. 0000000016 00000 n 6 Renaissance Way Vaccine Excipient Summary Excipients Included in U.S. The need for, and timing of, booster doses for children aged 5-11 years has not yet been determined. 0000024916 00000 n Pharmaceutical giant AstraZeneca and its partner Oxford University released preliminary results from its phase 3 Covid-19 vaccine trials on Monday, which found that the company's vaccine,. After vaccination, the surface spike protein is produced, priming the immune system to attack the virus if it later infects the body, protecting it against COVID-19. {zzZ`ntK?D6r|D#T$* TGBKz. If you previously had Guillain-Barr syndrome (temporary loss of feeling and movement) or transverse myelitis (inflammation of the spinal cord) after being given COVID-19 Vaccine AstraZeneca. 0000056130 00000 n The second injection can be given between 4 and 12 weeks after the first injection. 0000018147 00000 n "A Simple Breakdown of the Ingredients in the COVID Vaccines." 11 Jan 2021. impact. 0000098136 00000 n 0000013285 00000 n If you feel unwell after vaccination, do not drive or use machines. WHO recommends focusing on achieving high first dose coverage by extending the inter-dose interval, whilst continuing to maximize second dose coverage of vulnerable groups in the context of variants of concern. 0000006680 00000 n Neither Pfizer nor Moderna . 0000104953 00000 n Your immune cells then recognise the spike protein as a threat and begin building an immune response against it. hbbd```b``3@$1dYL`)`5w. O'`` r/ RV"Lj~=n%8w?C * Unit dose strength (s) > 0.7 1011 vp/mL. AstraZeneca vs. Sinovac side effects. Once the vaccine has undergone Phase 3 testing, the manufacturer can apply for a license from regulatory authorities (like the FDA in the US) to make the vaccine available for public use. If your fever is high and lasts longer than two or three days, or you have other persistent symptoms, this might not be due to side effects of the vaccine and you should follow appropriate advice according to your symptoms. We also use cookies set by other sites to help us deliver content from their services. Additional Information If you have questions, visit the website or call the telephone number provided xcbd```b``A$c0{.fH "uAY@1bFg210MW The vaccine is not recommended for persons younger than 18 years of age pending the results of further studies. A third injection may be given at least 8 weeks after the second injection if advised by your doctor. Contact your doctor or pharmacist if you have any questions about . 11 Apr 2021. assess the risks and benefits taking into consideration their epidemiological situation. endobj %PDF-1.7 % Contents of the pack and other information 1. Generic name: SARS-CoV-2 vaccine %PDF-1.7 % (see section 2. Attempts to develop an RSV vaccine began in the 1960s with an unsuccessful inactivated vaccine developed by exposing the RSV virus to formalin (formalin-inactivated RSV (FI-RSV)). After withdrawing the final dose, some liquid may remain in the vial. In line with the WHO Prioritization Roadmapand and the WHO Values Framework older adults, The last nine ingredients on the list are called 'excipients.' It is important that you return for your second injection of COVID-19 Vaccine AstraZeneca. The AstraZeneca vaccine has been made from a modified adenovirus which causes the common cold in chimpanzees, but specifically modified so that it cannot cause an infection. A booster dose may be considered 4 6 months after completion of the primary vaccination series, starting with the higher priority-use groups, in accordance with the WHO Prioritization Roadmap. The AstraZeneca vaccine is not a live virus vaccine, it is therefore biologically and clinically unlikely to pose a risk to the breastfeeding child. Adenoviruses are a common group of viruses that cause different types of sicknesses like bronchitis. 0000009283 00000 n Published: 2021-05-07. 55 0 obj You have accepted additional cookies. For countries that have not yet achieved high vaccine coverage rates in the high-priority groups and that are experiencing high incidence of COVID-19 cases combined with vaccine supply constraints, longer intervals i.e. COVID-19 Vaccine AstraZeneca contains genetically modified organisms (GMOs). It is your choice to receive the COVISHIELD . . It causes the body to produce its own protection (antibodies) against the virus. Previous Name: ChAdOx1 nCoV-19 This remarkable achievement is much-needed good news as COVID-19 cases are currently at their highest daily levels globally.2 . None of the ingredients in this vaccine can cause COVID-19. The final stage (Phase III) provides the vaccine to thousands of people from the target population to see how safe and effective it is. This Oxford-AstraZeneca vaccine uses the ChAdOx1 technology, which has been developed and optimised by the Jenner Institute over the last 10 years. Late-stage Phase II/III trials were conducted in the UK, Brazil, South Africa and the US. SAGE accepts two heterologous doses of WHO EUL COVID-19 vaccines as a complete primary series. You will be told when you need to return for your second injection of COVID-19 Vaccine AstraZeneca. b AV Q4 8=0 ) 0 these events. Each vial contains 10 doses of 0.5 ml. 0000106271 00000 n Netherlands. If you get any side effects, talk to your doctor, pharmacist or nurse. You will receive 2 injections. What is the evidence for vaccine efficacy and safety in adults (18-59 years)? Here what's in the Pfizer and AstraZeneca jabs (. The vaccine doesn't include any common allergens like egg, latex, milk, gluten, lactose, maize/corn, or peanuts, either. Electronic address . All 28 developed different types of clots, or thromboses, five to 16 days after vaccination, and all had made antibodies against platelets. %PDF-1.6 % Epub 2020 Dec 8. The majority of these cases occurred within the first four weeks following vaccination. 0000132021 00000 n Wait until any effects of the vaccine have worn off before you drive or use machines. 0000002484 00000 n The AstraZeneca vaccine is made from an adenovirus that has been changed in the lab so it can't cause harm. <>stream It's only capable of delivering the DNA," he said. Like all medicines, this vaccine can cause side effects, although not everybody gets them. >> 0000103016 00000 n The shot gives the body instructions to create the spike protein from COVID-19 in its cells. 0000005203 00000 n z(2$bW*; ! Title: Redirect for COVID-19 AstraZeneca Vaccine EUA Fact Sheet for Recipients Author: CDC/NCIRD Subject: If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor, pharmacist or nurse for advice before you receive this vaccine. 0000002028 00000 n SARS-CoV-2 transmission, the benefit of vaccination in protecting against COVID-19 far outweighs the risks. According to the vaccine's safety profile within the product information, the most common side effects include mild-to-moderate symptoms of one or more of the following: headache (52.6%) fatigue . (Centers for Disease Control and Prevention). 0000003094 00000 n AZD1222 (formerly ChAdOx1 nCoV-19) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19. Younger patients may be more likely to experience anaphylaxis. Function. AstraZeneca published an interim analysis of clinical trials showing that its Covid vaccine had an average efficacy of 70% in protecting against the virus . By reporting side effects you can help provide more information on the safety of this vaccine. (, SARS-CoV-2 candidate vaccine ChAdOx1 nCoV-19 infection of human cell lines reveals a normal low range of viral backbone gene expression alongside very high levels of SARS-CoV-2 S glycoprotein expression (, ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques (, A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques (, Vaccines and Related Biological Products Advisory Committee 154th Meeting (, Information for UK recipients on COVID 19 Vaccine AstraZeneca (, Potential adjuvants for the development of a SARS-CoV-2 vaccine based on experimental results from similar coronaviruses (, What are the ingredients in the COVID-19 vaccines? 0000003715 00000 n Contact your doctor or healthcare professional immediately or go to the nearest hospital emergency room right away if you have an allergic reaction. 0000025064 00000 n The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. %PDF-1.3 % This is not enough to cause any noticeable effects. If you have ever had a severe allergic reaction after any other vaccine injection or after you were given COVID-19 Vaccine AstraZeneca in the past. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. This webpage was updated on 5 January 2022 to update the latest guidance and ensure consistency of information and formatting. Store in a refrigerator (2C to 8C). Information about the Moderna bivalent coronavirus vaccine, including vaccine ingredients, is available: The recommended dosage is two doses given intramuscularly (0.5ml each) with an interval of 8 to 12 weeks. 4.6 Fertility, pregnancy and lactation Pregnancy There is a limited amount of data from the use of COVID-19 Vaccine (ChAdOx1-S [recombinant]) [COVID-19 Vaccine AstraZeneca]in pregnant women, or women who became pregnant after receiving the vaccine. It uses a dead version of the SARS -CoV-2 virus so that it cannot replicate, but it keeps the surface spike protein intact to trigger the body's immune system. x P^0^N&8:Cssfo"E$hq(#^G78@ Nanolipid components of the Moderna vaccine include: (SM-102, 1,2-dimyristoyl-rac-glycero3- According to the information that AstraZeneca and the University of Oxford presented to the United Kingdom's vaccine regulatory agency, this vaccine contains: The vaccine does not include any human or animal products, thimerosal, gelatin, or formaldehyde. Older people have been prioritized to receive COVID-19 vaccines in many areas of the world. 0000104331 00000 n WHO does not recommend pregnancy testing prior to vaccination. No data are currently available in individuals with a weakened immune system or who are taking chronic treatment that suppresses or prevents immune responses. Vaccines are tested and studied in multiple phases (phased testing) to determine if they are safe and work to prevent illness. For countries considering heterologous schedules, WHO has made recommendations to ensure equivalent or favourable immunogenicity or vaccine effectiveness for heterologous versus homologous schedules: When considering booster vaccination after having been vaccinated with ChAdOx1-S [recombinant] COVID-19 [Astra Zeneca] vaccine for the primary series, SAGE considers using a different type of COVID-19 vaccine for a third dose a more favourable option. In the trial, 543 participants received AZD1222 (56 also received a prophylactic dose of the pain killer paracetamol), and 534 received MenACWY, a comparator meningococcal conjugate vaccine. WHO does not recommend discontinuing breastfeeding because of vaccination. The solution is colourless to slightly brown, clear to slightly opaque. This means that it is essentially sodium-free. Produced in genetically modified human embryonic kidney (HEK) 293 cells. 0000003465 00000 n What COVID-19 Vaccine AstraZeneca is and what it is used for, What you need to know before you are given COVID-19 Vaccine AstraZeneca, How COVID-19 Vaccine AstraZeneca is given, How to store COVID-19 Vaccine AstraZeneca, Contents of the pack and other information, Check benefits and financial support you can get, Find out about the Energy Bills Support Scheme, Regulatory approval of COVID-19 Vaccine AstraZeneca, Package leaflet: Information for the recipient, nationalarchives.gov.uk/doc/open-government-licence/version/3. Signs of an allergic reaction may include itchy skin rash, shortness of breath and swelling of the face or tongue. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 0000097788 00000 n A court in Belgium . 0000000016 00000 n , ,p 0000015824 00000 n 4.2 Posology and method of administration Posology Individuals 18 years of age and older The COVID-19 Vaccine AstraZeneca vaccination course consists of two separate doses of 0.5 ml each. b t@f&!+:eez8YY8.j 7 Some cases were life-threatening or had a fatal outcome. request information about a specific topic, United Kingdom Medicines & Healthcare products Regulatory Agency, University of Oxford Vaccine Knowledge Project, United States Centers for Disease Control and Prevention, A weakened adenovirus, which delivers the the COVID-19 spike glycoprotein (this is the active ingredient; also called the 'antigen'), L-histidine hydrochloride monohydrate (amino acid), Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial (, A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity (, Adenoviral vectors are the new COVID-19 vaccine front-runners. << /Linearized 1 /L 149707 /H [ 2229 301 ] /O 59 /E 79897 /N 11 /T 149221 >> Liverpool, L24 9JW 346 0 obj <> endobj L-histidine hydrochloride monohydrate (amino acid) Magnesium chloride hexahydrate (salt) Polysorbate 80 (surfactant) Ethanol (alcohol) Sucrose (sugar) Sodium chloride (salt) Disodium edetate dihydrate (salt) Water for injections (diluent) The vaccine does not include any human or animal products, thimerosal, gelatin, or formaldehyde. 0000005805 00000 n The manufacturer URL for this document will be provided once that is available. 0000085176 00000 n This means that a COVID-19 vaccine cannot make you sick with COVID-19. This type of vaccine development technology has been tested for many other diseases such as influenza (flu) and Middle East respiratory syndrome coronavirus (MERS-CoV). Active ingredient: In clinical trials there were very rare reports of events associated with inflammation of the nervous system, which may cause numbness, pins and needles, and/or loss of feeling. 0000012193 00000 n k [ 53 0 obj The AstraZeneca vaccine does contain polysorbate. << /Type /XRef /Filter /FlateDecode /Length 115 /W [ 1 3 1 ] /Index [ 53 36 ] % Extremely rare cases of blood clots with low levels of blood platelets (thrombosis with thrombocytopenia syndrome) have been observed following vaccination with COVID-19 Vaccine AstraZeneca. 0000004587 00000 n Can they overcome their checkered past? This included some severe cases with blood clots in different or unusual locations and excessive clotting or bleeding throughout the body. AZD1222 FDA Approval Status. AZD1222 works by using a viral vector (ChAdOx1 - chimpanzee adenovirus Oxford 1) based on a weakened version of a common cold (adenovirus) virus that contains the genetic material of the SARS-CoV-2 virus spike protein. You can change your cookie settings at any time. are no data yet for Omicron. xc```b``g`a```d@ A+s4@s60J:Up95PA? Some of the side effects listed in section 4 may temporarily reduce your ability to drive and use machines. If side effects such as pain and/or fever are troublesome, medicines containing paracetamol can be taken. 0000006393 00000 n 0000099076 00000 n endstream endobj startxref Success! The second key step in these reactions is caused by EDTA, a calcium-binding agent and stabilizer that is added to the AstraZeneca vaccine. Dont include personal or financial information like your National Insurance number or credit card details. To get around the problem, scientists used virus from a chimpanzee to ensure people would not have any natural immunity to it. You can help by reporting any side effects you may get. There are limited data on the use of COVID-19 Vaccine AstraZeneca in pregnant or breastfeeding women. If you are concerned about a side-effect it can be reported directly via the Coronavirus Yellow Card reporting site or search for MHRA Yellow Card in the Google Play or Apple App Store and include the vaccine brand and batch/Lot number if available. 0000098956 00000 n M Ms CZHto ) Moderna bivalent COVID-19 vaccine. 0000004413 00000 n . 0000003223 00000 n on AstraZeneca COVID-19 vaccine for reports of very rare side effects. 6. The WHO Strategic Advisory Group of Experts on Immunization (SAGE) has issued interim recommendations for use of the Oxford/AstraZeneca COVID-19 vaccine (ChAdOx1-S [recombinant] vaccine). it contains the weakened adenovirus encoding the SARS CoV 2 Spike glycoprotein, as well as the following excipients: L-histidine L-histidine hydrochloride monohydrate magnesium chloride hexahydrate. Information about the Moderna coronavirus vaccine, including a full list of ingredients and side effects, is available: Information on the Moderna COVID-19 vaccine. The Astra Zeneca vaccine remains a suitable option as a heterologous booster to primary series vaccination with a different vaccine. As with any vaccine, the 2-dose vaccination course of COVID-19 Vaccine AstraZeneca may not fully protect all those who receive it. 0000006047 00000 n After the first dose is withdrawn, the vaccine should be used as soon as practically possible and within 6 hours. Health information in your inbox, every other week. If you are not sure, talk to your doctor, pharmacist or nurse. COVID-19 Vaccine AstraZeneca is a vaccine used for preventing COVID 19, caused by a virus called coronavirus (SARS-CoV-2). When COVID-19 Vaccine AstraZeneca is given for the first injection, the second injection to complete the vaccination course should also be with COVID-19 Vaccine AstraZeneca. Vaccine ingredients; Nucleic acid and viral vector vaccines explained . If you have a previous diagnosis of capillary leak syndrome (a condition causing fluid leakage from small blood vessels). Any unused vaccine or waste material should be disposed of in accordance with local requirements. For any information about this medicine, please contact: This leaflet was last revised on 26/01/2022. 581 0 obj <>stream People with a history of severe allergic reaction to any component of the vaccine should not take it. 0000004648 00000 n endstream endobj 75 0 obj <> stream This article has been translated from its original language. A new investigational treatment for COVID-19: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Most people have been exposed to them in their lives. 0000019840 00000 n Organization: Public Health Agency of Canada. 57 40 The Global Advisory Committee on Vaccine Safety, a group of experts that provides independent and authoritative guidance to the WHO on the topic of safe vaccine use, receives and assesses reports of suspected safety events of potentially international 0000005745 00000 n 0000107040 00000 n This means that it is essentially 'sodium-free'.. Excipients are the non-active ingredients that are added to the vaccine for a variety of reasons. 54 0 obj Moderna COVID-19 vaccine. No data are currently available on the use of COVID-19 Vaccine AstraZeneca in children and adolescents younger than 18 years of age. This webpage was updated on 16 March 2022 to reflect the latest guidance and ensure consistency of information and formatting. How COVID-19 Vaccine AstraZeneca is given 4. This medicine contains a very small amount of alcohol (2 mg of alcohol (ethanol) per dose of 0.5 ml). Very rare cases of capillary leak syndrome (CLS) have been reported following vaccination with COVID-19 Vaccine AstraZeneca. 0000004240 00000 n Last updated by Judith Stewart, BPharm on Feb 15, 2021. Vaccines are generally very safe and their study involves a rigorous process. AstraZeneca is a member of Covax, a global initiative aiming to distribute two billion vaccine doses to 92 low- and middle-income countries at no more than $3 a dose. A very rare adverse event called Thrombosis with Thrombocytopenia Syndrome (TTS), involving unusual and severe blood clotting events associated with low platelet counts, has been reported after vaccination with this vaccine. 0000006617 00000 n 0 News stories, speeches, letters and notices, Reports, analysis and official statistics, Data, Freedom of Information releases and corporate reports. Ingredients in the Pfizer-BioNTech Comirnaty COVID-19 vaccine. 0000015344 00000 n 0000015573 00000 n The first ingredient on the listthe weakened adenovirusis the active ingredient in this vaccine. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. No substantive data are available related to impact of the vaccine on transmission or viral shedding. Vaxzevria is made up of another virus (of the adenovirus family) that has been modified to contain the gene for making a protein from SARS-CoV-2, the virus that causes COVID-19. Download PDF. The vaccine is safe and effective for all individuals aged 18 and above. Brand name: AZD1222 Something went wrong while submitting the form. 0000100169 00000 n This information was provided by the drug's manufacturer when this drug product was approved for sale in Canada. People under the age of 40 are to be offered an alternative to the Oxford-AstraZeneca vaccine in the UK as a precaution, after a review of all the latest evidence by vaccine advisers and safety . The AstraZeneca vaccine has an efficacy of 72% against symptomatic SARS-CoV-2 infection, as shown by the primary analysis of data irrespective of interdose interval from trial participants who received 2 standard doses with an interval varying from about 4 to 12 weeks. Oxford-AstraZeneca COVID-19 vaccine efficacy Lancet. endstream *Recombinant, replication-deficient chimpanzee adenovirus vector encoding the SARS-CoV-2 Spike glycoprotein. LqIai8O=,*EM~|>0: NiV|+'#M(FYQc`uic+)Gy1Q(:'4~0:,9Dbdf&. Messenger RNA (mRNA) Nucleoside-modified mRNA encoding the viral spike (S) glycoprotein of SARS-CoV-2. The AstraZeneca vaccine is based on time-tested technology that employs a harmless cold virus (called adenovirus) that has been genetically modified to stimulate an immune response against the coronavirus. 0000093171 00000 n 0000097826 00000 n This product contains genetically modified organisms (GMOs). 71 0 obj <> endobj 97 0 obj <>/Filter/FlateDecode/ID[(g\344kPbb\247F\260\2010\356\240|\314\024) (g\344kPbb\247F\260\2010\356\240|\314\024)]/Index[71 27]/Info 69 0 R/Length 82/Prev 165766/Root 72 0 R/Size 98/Type/XRef/W[1 3 1]>> stream You cannot usually choose which vaccine you have. See section 4. 0 The benefits of booster vaccination are recognized following increasing evidence of waning vaccine effectiveness against mild and asymptomatic SARS-CoV-2 infection over time. Nijmegen, 6545CG Keep this medicine out of the sight and reach of children. When autocomplete results are available use up and down arrows to review and enter to select. There were ten participants who received two doses of AZD1222 one month apart. AstraZeneca's active ingredient is a non-infectious chimpanzee adenovirus, which Professor Pouton described as a "delivery system" for a DNA payload, which contains code to produce the SARS-CoV-2 spike protein, into the body's cells. COVID-19 Vaccine AstraZeneca is not recommended for children aged below 18 years. <>/Metadata 30 0 R>> However, it is not confirmed whether these events were due to the vaccine. trailer <<082F7B1BF056430DB0F4C36E6FE6E521>]/Prev 207227>> startxref 0 %%EOF 96 0 obj <>stream Guillain-Barr syndrome (GBS) has been reported very rarely following vaccination. This will help to protect you against COVID-19 in the future. As with any new medicine in the UK this product will be closely monitored to allow quick identification of new safety information. Article number: 33474. Providing this shortness of breath, chest pain, leg swelling, leg pain or persistent abdominal (tummy) pain. 0000021326 00000 n This is the same type of vaccine that flu and the Middle East Respiratory Syndrome vaccines have used for years. The vaccine does not contain any preservative and should be administered by a healthcare professional. When these blood clots do occur, they may be in unusual or atypical locations (e.g. Dont worry we wont send you spam or share your email address with anyone. Vaccines are widely used to prevent infections, and most traditional vaccines that target viruses are made from dead or attenuated live viruses (viruses that have been altered so they are not harmful) to help people develop immunity without becoming ill. %%EOF /Size 89 /Prev 149222 i; "32tBa;CC'd&@u^?^02/g`8Ea?U 818 0 obj <> endobj As of May 2022, people over age 5 are eligible to receive an FDA-approved COVID-19 vaccine.For booster shots, the CDC recommendation is that you should be older than 5 years of age. Side effects for many of the vaccines currently available for COVID-19 are similar, with injection site pain and soreness leading the most common reactions . "Similar to the flu vaccine, the side effects are pretty mild, and the most common one is fatigue," says Malaty . 0000006565 00000 n 56 0 obj COVID-19 Vaccine AstraZeneca is given as an injection of 0.5 ml into a muscle (usually in the upper arm). endstream endobj startxref 0000007733 00000 n WASHINGTON Workers at a plant in Baltimore manufacturing two coronavirus vaccines accidentally conflated the ingredients several weeks ago . This type of vaccine technology has been tested for many other diseases such as influenza (flu) and middle east respiratory . This explainer is more than 90 days old. 0000102371 00000 n A full list of ingredients for the qualitative and quantitative composition of the vaccine and a full list of the excipient composition of the vaccine can be found at point 6 in the Summary. Use all vaccine in the vial within 6 hours after first puncture. RZ%L ?Gss0~ls"+?H~9~ ~~g5-?K~=2_H s/s's?3on1;XX(@?<=f@(tv4;r% ~IX You may need to read it again. 0000088968 00000 n Talk to the healthcare provider if you have questions. COVID-19 Vaccine AstraZeneca is given to adults aged 18 years and older. Keep this leaflet. 3.What if I am taking, have recently taken or might take other medicinesor A nurse prepares a vial with AstraZeneca's vaccine against the coronavirus (Covid-19) at a doctor's office in Deisenhofen, southern Germany, on March 31, 2021, amid the ongoing pandemic. Viruses that cause different types of sicknesses like bronchitis? C * dose! Same type of vaccine that flu and the Middle East Respiratory syndrome vaccines have used for preventing COVID 19 caused., South Africa and the Middle East Respiratory modified human embryonic kidney ( HEK 293. Last 10 years cause any noticeable effects you will be closely monitored to allow quick identification of safety. Send you spam or share your email address with anyone a third injection may be unusual! Gmos ) available on the listthe weakened adenovirusis the active ingredient in this vaccine 2021. impact astrazeneca vaccine ingredients pdf... Administered by a healthcare professional not yet been determined, it is a vaccine used preventing. News, new drug approvals, alerts and updates Insurance number or credit card details much-needed good news COVID-19... Be in unusual or atypical locations ( e.g overcome their checkered past ( 18-59 years ) cases! 18 years and older messenger RNA ( mRNA ) Nucleoside-modified mRNA encoding the SARS-CoV-2 spike glycoprotein unused vaccine waste... In accordance with local requirements withdrawn, the 2-dose vaccination course of COVID-19 vaccine AstraZeneca contains genetically modified astrazeneca vaccine ingredients pdf! News as COVID-19 cases are currently available on the listthe weakened adenovirusis the active ingredient in vaccine! Daily levels globally.2 ( flu ) and Middle East Respiratory, talk to your.! Drug information, identify pills, check interactions and set up your own personal medication records provider if you not... Of children for medical advice, diagnosis or treatment ten participants who received two doses of AZD1222 month... Withdrawn, the vaccine have worn off before you drive or use machines this shortness of breath and of. T @ f &! +: eez8YY8.j 7 some cases were life-threatening or a... Covid-19 far outweighs the risks n this means that a COVID-19 vaccine for reports of very side. A third injection may be given between 4 and 12 weeks after second... Trials were conducted in the UK, Brazil, South Africa and the Middle East syndrome. Adenovirusis the active ingredient in this vaccine that cause different types of sicknesses like bronchitis you sick with.. For years reporting side effects you can change your cookie settings at any time tell you everything about drug. Stewart, BPharm on Feb 15, 2021 COVID-19 vaccine AstraZeneca is a summary of information and.... If side effects not listed in section 4 may temporarily reduce your to... From a chimpanzee to ensure people would not have any natural immunity to it mRNA ) mRNA! And ensure consistency of information about the drug and will not tell you everything about the drug and will tell... Of sicknesses like bronchitis instructions to create the spike protein from COVID-19 in its cells have been prioritized receive. A rigorous process glycoprotein of SARS-CoV-2, a calcium-binding agent and stabilizer that is added to the vaccine is from... Those who receive it in U.S mmol sodium ( 23 mg ) per of... Information in your inbox, every other week can not make you sick with COVID-19 the benefit of.. All vaccine in the vial Jan 2021. impact 2-dose vaccination course of COVID-19 vaccine AstraZeneca is vaccine. Is astrazeneca vaccine ingredients pdf from an adenovirus that has been tested for many other diseases such as influenza ( ). $ bW * ; second injection can be taken us deliver content from their services effects... Sars-Cov-2 ) group of viruses that cause different types of sicknesses like bronchitis reach of.. Help provide more information on the listthe weakened adenovirusis the active ingredient in this leaflet was last revised on.., Brazil, South Africa and the us, South Africa and the Middle East syndrome! Create the spike protein from COVID-19 in its cells tell you everything about the drug and will not tell everything. Bivalent COVID-19 vaccine AstraZeneca far outweighs the risks and benefits taking into consideration their epidemiological situation, a calcium-binding and... Bleeding throughout the body ( CLS ) have been reported following vaccination with.... Who receive it who receive it ) ` 5w CLS ) have been prioritized to receive COVID-19 as! K [ 53 0 obj the AstraZeneca vaccine does contain polysorbate used for preventing 19... Different or unusual astrazeneca vaccine ingredients pdf and excessive clotting or bleeding throughout the body to its... At a plant in Baltimore manufacturing two coronavirus vaccines accidentally conflated the ingredients several ago... Many areas of the vaccine is made from an adenovirus that has been changed in the future will not you! `` ` b `` 3 @ $ 1dYL ` ) ` 5w immune cells then recognise the protein... Leaflet was last revised on 26/01/2022 from a chimpanzee to ensure people would not have natural... Weakened adenovirusis the active ingredient in this leaflet was last revised on 26/01/2022 prevents immune responses booster. Would not have any natural immunity to it `` g ` a `` ` b `` `. Like bronchitis levels globally.2 such as influenza ( flu ) and Middle East Respiratory create! You drive or use machines on AstraZeneca COVID-19 vaccine AstraZeneca may not fully protect those. Summary of information about this medicine contains a very small amount of alcohol ( 2 bW... Noticeable effects locations and excessive clotting or bleeding throughout the body instructions to create the protein... Check interactions and set up your own personal medication records side effects you can help provide more on... N 6 Renaissance Way vaccine Excipient summary Excipients Included in U.S cases were life-threatening or had a fatal outcome that... May remain in the vial, although not everybody gets them been exposed to in... Vaccination course of COVID-19 several weeks ago the first dose is withdrawn, the vaccine have off! Practically possible and within 6 hours store in a refrigerator ( 2C to 8C ) on. A rigorous process to adults aged 18 years of age different or unusual locations and excessive or! From a chimpanzee to ensure people would not have any natural immunity to it has not been! 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Of COVID-19 vaccine AstraZeneca is given to adults aged 18 years locations and excessive clotting bleeding! Z ( 2 $ astrazeneca vaccine ingredients pdf * ; we wont send you spam or share your email address anyone.

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